ESPHome & the TinyPICO RGB LED

Yes, you can definitely use the APA102 RGB LED on the TinyPICO in ESPHome.

The code you need to set it up is:

power_supply:
    id: rgb_led_power
    pin:
      number: GPIO13
      inverted: true

light:
  - platform: fastled_spi
    id: rgb_led
    chipset: APA102
    data_pin: GPIO2
    clock_pin: GPIO12
    num_leds: 1
    rgb_order: BGR
    name: "RGB LED"
    restore_mode: RESTORE_DEFAULT_OFF
    power_supply: rgb_led_power

Which will give you the following results:

ESPHome RGB LED control

ESPHome RGB LED settings

Images & settings provided by Jonny Bergahl